The organism typically colonizes the infant gastrointestinal tract within hours of life, and, thereafter, E. coli strains and describes how their pathogenic schemes underlie the clinical manifestations, diagnostic approach, and epidemiologic investigation of these important pathogens.Įscherichia coli is the predominant facultative anaerobe of the human colonic flora. This review discusses the current level of understanding of the pathogenesis of the diarrheagenic E. coli), and watery diarrhea of infants (enteropathogenic E. coli), persistent diarrhea (enteroaggregative E. coli), hemorrhagic colitis and hemolytic-uremic syndrome (enterohemorrhagic E. coli categories, including traveler’s diarrhea (enterotoxigenic E. Several distinct clinical syndromes accompany infection with diarrheagenic E. Taken together, these organisms probably represent the most common cause of pediatric diarrhea worldwide. coli can be divided into at least six different categories with corresponding distinct pathogenic schemes. coli strains, however, have developed the ability to cause disease of the gastrointestinal, urinary, or central nervous system in even the most robust human hosts. Escherichia coli is the predominant nonpathogenic facultative flora of the human intestine.
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